******************************* Acknowledgements ******************************* We thank `The Lobo Lab `_ for their help with software testing and The University of Maryland Baltimore County for its resources and support. We also thank the following packages and databases for their public resources: #. `COBRApy `_ #. `Click `_ #. `ModelSEED `_ #. `KBase `_ #. `MetaNetX `_ #. `KEGG `_ #. `ChEBI `_